Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development.

Development (Cambridge, England) - 1 Sept 1993

Mann S K, Firtel R A

Abstract excerpt

We and others have previously shown that cAMP-dependent protein kinase (PKA) activity is essential for aggregation, induction of prespore gene expression and multicellular development in Dictyostelium. In this manuscript, we further examine this regulatory role. We have overexpressed the Dictyostelium PKA catalytic subunit (PKAcat) in specific cell types during the multicellular stages, using prestalk and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Dictyostelium
Share to Morphogenesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Protein Kinases

Source

Identifiers

PMID: 8275851
DOI: 10.1242/dev.119.1.135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development.PMID 8275851Read ↗

Multiple roles for cAMP-dependent protein kinase during Dictyostelium development.Semantic proximity Read ↗

cAMP production by adenylyl cyclase G induces prespore differentiation in Dictyostelium slugs.Semantic proximity Read ↗

A conserved signalling pathway for amoebozoan encystation that was co-opted for multicellular development.Semantic proximity Read ↗

A Dictyostelium anterior-like cell mutant reveals sequential steps in the prespore prestalk differentiation pathway.Semantic proximity Read ↗

Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum.Semantic proximity Read ↗

A role for cAMP-dependent protein kinase A in early Dictyostelium development.Semantic proximity Read ↗

Activation of the prespore and spore cell pathway of Dictyostelium differentiation by cAMP-dependent protein kinase and evidence for its upstream regulation by ammonia.Semantic proximity Read ↗

Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium.Semantic proximity Read ↗

Cyclic AMP induction of Dictyostelium prespore gene expression requires autophagySemantic proximity Read ↗

Loss of cAMP-specific phosphodiesterase rescues spore development in G protein mutant in dictyostelium.Semantic proximity Read ↗

Cell-type-specific rescue of myosin function during Dictyostelium development defines two distinct cell movements required for culmination.Semantic proximity Read ↗

Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.