Article
Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum.
Developmental biology - 15 Jan 1998
Anjard C, Zeng C, Loomis W F, Nellen W
Abstract excerpt
Cells that overexpress PKA as a consequence of carrying multiple copies of the gene encoding the catalytic subunit can be induced to sporulate when developing as single cells. A peptide phosphorylated by PKA, termed SDF-1, has recently been shown to stimulate this process (Anjard et al., 1997). Several genes have been implicated in a signal transduction pathway by which prestalk cells induce encapsulation of...
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