Article
Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum.
Developmental biology - 15 Jan 1998
Anjard C, Zeng C, Loomis W F, Nellen W
Abstract excerpt
Cells that overexpress PKA as a consequence of carrying multiple copies of the gene encoding the catalytic subunit can be induced to sporulate when developing as single cells. A peptide phosphorylated by PKA, termed SDF-1, has recently been shown to stimulate this process (Anjard et al., 1997). Several genes have been implicated in a signal transduction pathway by which prestalk cells induce encapsulation of...
Topics
- Animals
- Cells, Cultured
- Chemokine CXCL12
- Chemokines
- Chemokines, CXC
- Cyclic AMP-Dependent Protein Kinases
- Dictyostelium
- Endopeptidases
- Fungal Proteins
- Intercellular Signaling Peptides and Proteins
- Membrane Proteins
- Mutation
- Peptides
- Protein Kinases
- Proteins
- Signal Transduction
- Spores, Fungal
