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Article

UV-induced N-ras mutations are T-cell targets in human melanoma.

Melanoma research - 1 Aug 1997

van Elsas A, Scheibenbogen C, van der Minne C, Zerp S F, Keilholz U, Schrier P I

Abstract excerpt

Human cutaneous melanoma is heterogeneous with respect to the genetic aberrations involved and the genes altered are potential targets for the immune system. The incidence of cutaneous melanoma is known to be linked to UV peak exposure, and the N-ras oncogene is clearly one of the genes involved in the UV carcinogenesis in melanoma. It is mutated in a significant proportion of melanomas and therefore may serve as...

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PMID: 9578425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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