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Article

CTLA4 variants, UV-induced tolerance, and risk of non-melanoma skin cancer.

Cancer research - 1 Aug 2009

Welsh Marleen M, Applebaum Katie M, Spencer Steven K, Perry Ann E, Karagas Margaret R, Nelson Heather H

Abstract excerpt

Although skin tumors are highly immunogenic, exposure to UV radiation is known to suppress immune responses via regulatory T cells. Specifically, the activity of cytotoxic lymphocyte-associated antigen-4 (CTLA-4) is integral in regulating the development of UV-induced tolerance and, concomitantly...

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Share to Carcinoma, Basal Cell
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Share to CTLA-4 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19622768
DOI: 10.1158/0008-5472.CAN-09-0415
PMCID: PMC2928067

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19622768-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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