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Article

Identification of two Melan-A CD4+ T cell epitopes presented by frequently expressed MHC class II alleles.

Clinical immunology (Orlando, Fla.) - 1 Oct 2006

Godefroy Emmanuelle, Scotto Luigi, Souleimanian Naira E, Ritter Gerd, Old Lloyd J, Jotereau Francine, Valmori Danila, Ayyoub Maha

Abstract excerpt

Because of its expression pattern restricted to cells of the melanocytic lineage and to melanoma cells, Melan-A is an important target of immunotherapeutic approaches for the treatment of melanoma. Identification of Melan-A derived sequences recognized by specific T cells is therefore of great interest for the development of these therapeutic strategies. Using circulating CD4(+) T cells from healthy donors, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Epitopes, T-Lymphocyte

Share to Histocompatibility Antigens Class II

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Source

Identifiers

PMID: 16814609
DOI: 10.1016/j.clim.2006.05.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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