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Article

In vivo 6-thioguanine-resistant T cells from melanoma patients have public TCR and share TCR beta amino acid sequences with melanoma-reactive T cells.

Journal of immunological methods - 28 Feb 2011

Zuleger Cindy L, Macklin Michael D, Bostwick Bret L, Pei Qinglin, Newton Michael A, Albertini Mark R

Abstract excerpt

In vivo hypoxanthine-guanine phosphoribosyltransferase (HPRT)-deficient T cells (MT) from melanoma patients are enriched for T cells with in vivo clonal amplifications that traffic between blood and tumor tissues. Melanoma is thus a model cancer to test the hypothesis that in vivo MT from cancer...

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Share to Amino Acid Motifs
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Share to Genes, T-Cell Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxanthine Phosphoribosyltransferase

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Source

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Identifiers

PMID: 21182840
DOI: 10.1016/j.jim.2010.12.007
PMCID: PMC3035723

Genes

TRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21182840-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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