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Article

Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells.

Molecular immunology - 1 Jan 2000

Lunde E, Bogen B, Sandlie I

Abstract excerpt

Antibody (Ab) molecules may serve as targeting vehicles for delivery of foreign antigenic peptides to antigen presenting cells (APC). An attractive strategy is to substitute segments between beta-strands of immunoglobulin (Ig) constant (C)-region domains with antigenic peptides. For this to work,...

Topics

Amino Acid Sequence
Animals
Antigen Presentation
Antigens
Base Sequence
CD4-Positive T-Lymphocytes
CHO Cells
Cricetinae
Genes, Immunoglobulin
Humans
Immunoglobulins
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Antigen, T-Cell

Transfection

Source

Identifiers

PMID: 9566764
DOI: 10.1016/s0161-5890(97)00143-0

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9566764-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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