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Article

Generation of the germline peripheral B cell repertoire: VH81X-lambda B cells are unable to complete all developmental programs.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1998

Martin F, Won W J, Kearney J F

Abstract excerpt

The generation of VH81X heavy chain lambda-light chain-expressing B cells (VH81X-lambda+ B cells) was studied in VH81X heavy chain transgenic mice as well as in VH81X JH (-/-) and VH81X JH (-/-) Ck (-/-) mice, in which competition resulting from expression of heavy and light chains from the endogenous heavy and kappa light chain loci was prevented. We show that although lambda light chain gene rearrangements...

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PMID: 9558077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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