Article
Using information from both parents when testing for association between marker and disease loci.
Genetic epidemiology - 1 Jan 1998
Whittaker J C, Morris A P, Curnow R N
Abstract excerpt
Several extensions of the transmission/disequilibrium test (TDT) to multi-allelic markers now exist. In some of these, however, separate tests must be performed on male and female parents because of the non-independence of parental transmission patterns, reducing power, and complicating interpretation of the test results. Here we show that this non-independence is asymptotically irrelevant when using the allelic...
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