Article
A robust TDT-type association test under informative parental missingness.
Statistics in medicine - 10 Feb 2011
Chen J H, Cheng K F
Abstract excerpt
Many family-based association tests rely on the random transmission of alleles from parents to offspring. Among them, the transmission/disequilibrium test (TDT) may be considered to be the most popular statistical test. The TDT statistic and its variations were proposed to evaluate nonrandom transmission of alleles from parents to the diseased children. However, in family studies, parental genotypes may be...
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