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Article

A Bayesian approach to the transmission/disequilibrium test for binary traits.

Genetic epidemiology - 1 Jan 2002

George Varghese, Laud Purushottam W

Abstract excerpt

The transmission/disequilibrium test (TDT) for binary traits is a powerful method for detecting linkage between a marker locus and a trait locus in the presence of allelic association. The TDT uses information on the parent-to-offspring transmission status of the associated allele at the marker locus to assess linkage or association in the presence of the other, using one affected offspring from each set of...

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PMID: 11754472
DOI: 10.1002/gepi.1042

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