Article
Integrating case-control and TDT studies.
Annals of human genetics - 1 May 2005
Kazeem G R, Farrall M
Abstract excerpt
Genetic-association studies are widely expected to unravel the genetic basis of complex diseases. The population-based case-control study, a commonly used approach for association studies, is subject to the problem of population admixture. Consequently, evidence of disease-marker associations obtained from such studies is ideally confirmed by alternative methods. The Transmission/Disequilibrium Test (TDT) is...
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