Article
Transmission disequilibrium test (TDT) when only one parent is available: the 1-TDT.
American journal of epidemiology - 1 Jul 1999
Sun F, Flanders W D, Yang Q, Khoury M J
Abstract excerpt
The transmission disequilibrium test (TDT) is a useful method to locate mutations linked to disease genes associated with complex diseases. TDT requires genotypes of affected individuals and their parents. Recently, Ewens and Spielman (Am J Hum Genet 1998;62:450-8) extended the TDT for use in sibships with at least one affected and one unaffected individual and devised a new test called the sib...
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