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Article

Likelihoods and TDT for the case-parents design.

Genetic epidemiology - 1 Jan 1999

Schaid D J

Abstract excerpt

Association studies using diseased cases and their parents avoid biases due to population stratification, and the transmission/disequilibrium test (TDT) is a popular method of analysis. Sample size and power calculations for the TDT method have been reported, but often for the special situation of multiplicative effects of alleles on the genotype relative risks. Furthermore, some of the proposed calculations...

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PMID: 10096688
DOI: 10.1002/(SICI)1098-2272(1999)16:3<250::AID-GEPI2>3.0.CO;2-T

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