Article
Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers.
Genetic epidemiology - 1 Jan 1995
Bickeböller H, Clerget-Darpoux F
Abstract excerpt
The transmission/disequilibrium test (TDT) is extended in two ways for a multiallelic marker: (1) to compare transmitted and nontransmitted alleles from a single heterozygous parent and (2) to compare genotypes formed by the two transmitted alleles and genotypes formed by the two nontransmitted a...
Topics
- Alleles
- Female
- Gene Frequency
- Genetic Diseases, Inborn
- Genetic Markers
- Genotype
- Heterozygote
- Humans
- Linkage Disequilibrium
- Male
- Models, Genetic
- Models, Statistical
- Nuclear Family