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Article

Effects of FK506-binding protein 12 and FK506 on autophosphorylation of epidermal growth factor receptor.

The Journal of biological chemistry - 17 Apr 1998

Lopez-Ilasaca M, Schiene C, Küllertz G, Tradler T, Fischer G, Wetzker R

Abstract excerpt

FK506-binding proteins and cyclophilins are intracellular proteins that express peptidylproline cis-trans-isomerase (PPIase) activity. The effects of FK506-binding protein 12 (FKBP12) and the cyclophilins 18 and 23 on autophosphorylation of the epidermal growth factor (EGF) receptor prepared from plasma membranes of the human epidermoid cell line A431 have been investigated. Whereas FKBP12 inhibited EGF receptor...

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Source

Identifiers

PMID: 9545268
DOI: 10.1074/jbc.273.16.9430

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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