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Article

The immunophilin FKBP52 specifically binds to tubulin and prevents microtubule formation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2007

Chambraud Béatrice, Belabes Hamida, Fontaine-Lenoir Virginie, Fellous Arlette, Baulieu Etienne Emile

Abstract excerpt

The FK506 binding protein FKBP52 belongs to the large family of immunophilins and is known as a steroid receptor-associated protein. Previous data suggest that FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. Here we demonstrate a specific and direct interaction between FKBP52 and tubulin. The region of FKBP52 located between aa 267 and 400, which includes the...

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Source

Identifiers

PMID: 17435176
DOI: 10.1096/fj.06-7667com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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