Article
Determination of HPRT mutant frequency and molecular analysis of T-lymphocyte mutants derived from coke-oven workers.
Mutation research - 30 Jan 1998
Zanesi N, Mognato M, Pizzato M, Viezzer C, Ferri G, Celotti L
Abstract excerpt
We measured the frequency of mutant (MF) lymphocytes at the hprt locus in a population of 43 coke-oven workers exposed to PAH and in a group of 26 non-exposed workers. A non-significant increase in MF in the exposed group (19.0 +/- 16.3) compared to the non-exposed group (15.8 +/- 14.6) was obser...
Topics
- Adult
- Age Factors
- Coke
- DNA Mutational Analysis
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Industry
- Middle Aged
- Mutagens
- Mutation
- Occupational Exposure
- Polycyclic Aromatic Hydrocarbons
- Polymerase Chain Reaction
- T-Lymphocytes