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Article

Rapid characterization of mutations in amplified human hprt cDNA by polyacrylamide gel electrophoresis.

Mutation research - 1 Nov 1998

Garganta F, Krause G, Scherer G

Abstract excerpt

Compiling hprt mutation spectra involves the isolation and analysis of numerous 6-thioguanine-resistant clones for identifying characteristic point mutations. Since cDNA amplificates are compulsory intermediates in most mutant classification protocols, we suggest their preliminary characterization by polyacrylamide gel electrophoresis for the rapid distinction of clonal and independent mutants and for...

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PMID: 9920053
DOI: 10.1016/s1383-5726(98)00008-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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