Article
GSTM1 null genotype as a risk factor for anti-BPDE-DNA adduct formation in mononuclear white blood cells of coke-oven workers.
Mutation research - 14 Mar 2004
Pavanello Sofia, Siwinska Ewa, Mielzynska Danuta, Clonfero Erminio
Abstract excerpt
The influence of the genetic deletion polymorphism of glutathione S-transferase micro 1 (GSTM1 *0/*0) on levels of anti (+/-)-r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (anti-BPDE-DNA) adduct in the peripheral blood lymphocyte plus monocyte fraction (LMF) of coke-oven workers...
Topics
- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
- Adult
- Chromatography, High Pressure Liquid
- Coke
- DNA Adducts
- Genotype
- Glutathione Transferase
- Humans
- Male
- Middle Aged
- Monocytes
- Occupational Exposure
- Polymerase Chain Reaction
- Risk Factors
- Spectrometry, Fluorescence