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Article

Elevated hprt mutant frequency in circulating T-lymphocytes of xeroderma pigmentosum patients.

Mutation research - 1 Mar 1992

Cole J, Arlett C F, Norris P G, Stephens G, Waugh A P, Beare D M, Green M H

Abstract excerpt

The mutant frequency to 6-thioguanine resistance in circulating T-lymphocytes from 10 xeroderma pigmentosum patients (including complementation groups D and G and XP variants) has been determined. A highly significantly elevated frequency was observed, compared to age-matched, non-smoking control donors (x 2.1-fold higher than the mutant frequency in normal control donors, adjusted for age and cloning efficiency,...

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Source

Identifiers

PMID: 1372100
DOI: 10.1016/0921-8777(92)90078-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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