Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the IGF system and analysis of the possible molecular mechanisms leading to IGF-II overexpression in a mesothelioma.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Nov 1997

Hodzic D, Delacroix L, Willemsen P, Bensbaho K, Collette J, Broux R, Lefèbvre P, Legros J J, Grooteclaes M, Winkler R

Abstract excerpt

The expression of members of the IGF system in a mesothelioma from a patient suffering from hypoglycemia, in term placenta and HT29 colon adenocarcinoma cells were compared. Very high levels of IGF-II mRNA and protein were detected in the mesothelioma. Moreover, half of the IGF-II protein took the high-molecular-weight form. We also analyzed the parental imprinting status and the promoter usage of the IGF-II...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alleles

Share to Blotting, Northern

Share to Gene Expression

Share to Genomic Imprinting

Share to Insulin-Like Growth Factor II

Share to Mesothelioma

Source

Identifiers

PMID: 9479554
DOI: 10.1055/s-2007-979099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the IGF system and analysis of the possible molecular mechanisms leading to IGF-II overexpression in a mesothelioma.PMID 9479554Read ↗

Promoter-dependent tissue-specific expressive nature of imprinting gene, insulin-like growth factor II, in human tissues.Semantic proximity Read ↗

Selective Activation of Insulin Receptor Substrate-1 and -2 in Pleural Mesothelioma CellsSemantic proximity Read ↗

Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction.Semantic proximity Read ↗

Loss of imprinting of IGF2 in fibroadenomas and phyllodes tumors of the breast.Semantic proximity Read ↗

Disrupted IGF2 promoter control by silencing of promoter P1 in human hepatocellular carcinoma.Semantic proximity Read ↗

Alterations in the promoter-specific imprinting of the insulin-like growth factor-II gene in Wilms' tumor.Semantic proximity Read ↗

Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis.Semantic proximity Read ↗

Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting.Semantic proximity Read ↗

Purification and characterization of insulin-like growth factor II (IGF II) and an IGF II variant from human placenta.Semantic proximity Read ↗

Transcriptional regulation and biological significance of the insulin like growth factor II geneSemantic proximity Read ↗

Loss of imprinting of the IGF2 gene in a Wilms' tumor in an adult.Semantic proximity Read ↗

Loss of imprinting of human insulin-like growth factor II gene, IGF2, in acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.