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Article

Purification and characterization of insulin-like growth factor II (IGF II) and an IGF II variant from human placenta.

Journal of chromatography. B, Biomedical applications - 21 Apr 1995

De Ceuninck F, Willeput J, Corvol M

Abstract excerpt

In order to purify variant IGF II peptides from human placenta, we have developed a purification procedure combining heparin affinity chromatography and cation-exchange, reversed-phase and size-exclusion HPLC. Two peptides were purified, both having apparent M(r) values of ca. 7300 Da as evaluated by SDS-PAGE. N-Terminal sequencing revealed IGF II and an IGF II variant in which Ser29 was replaced by the...

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PMID: 7633596
DOI: 10.1016/0378-4347(94)00576-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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