Article
Loss of imprinting of human insulin-like growth factor II gene, IGF2, in acute myeloid leukemia.
Biochemical and biophysical research communications - 13 Feb 1997
Wu H K, Weksberg R, Minden M D, Squire J A
Abstract excerpt
Genomic imprinting is a non-Mendelian form of gene regulation resulting in differential allelic expression of a gene and plays an important role in the development of certain types of cancer and genetic diseases. Imprinting of IGF2 was demonstrated in normal placenta and fetal kidney by showing m...
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