Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction.

International journal of molecular medicine - 1 Oct 2011

Koukoura Ourania, Sifakis Stavros, Soufla Giannoula, Zaravinos Apostolos, Apostolidou Sophia, Jones Allison, Widschwendter Martin, Spandidos Demetrios A

Abstract excerpt

The objective of this study was to investigate the hypothesis that the altered epigenetic mechanisms that regulate IGF2 imprinting in placentas from fetal growth restricted (FGR) pregnancies affect IGF2 expression leading to impaired fetal growth. We investigated gene transcription, genotyping an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Fetal Growth Retardation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Genotype

Share to Insulin-Like Growth Factor II

Share to Placenta

Share to Pregnancy

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 21805044
DOI: 10.3892/ijmm.2011.754

Genes

IGF2
FGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21805044-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction.PMID 21805044Read ↗

Insulin-like growth factor axis in pregnancies affected by fetal growth disordersSemantic proximity Read ↗

IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restrictionSemantic proximity Read ↗

Investigating genetic factors associated with complications of pregnancySemantic proximity Read ↗

Epigenetic dysregulation of the IGF system in placenta of newborns exposed to maternal impaired glucose toleranceSemantic proximity Read ↗

Deregulation of imprinted genes expression and epigenetic regulators in placental tissue from intrauterine growth restrictionSemantic proximity Read ↗

Fetal growth restriction and methylation of growth-related genes in the placenta.Semantic proximity Read ↗

Differential expression of imprinted genes in normal and IUGR human placentas.Semantic proximity Read ↗

Placental-specific IGF-II is a major modulator of placental and fetal growth.Semantic proximity Read ↗

The role of imprinted genes in fetal growth abnormalitiesSemantic proximity Read ↗

Differential Methylation of Imprinted Genes in Growth-Restricted PlacentasSemantic proximity Read ↗

Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placentaSemantic proximity Read ↗

Fetal epigenetic programming of the IGF axis in pregnancies affected by growth disorders, gestational diabetes and obesitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.