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Article

Pathogenic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat.

Carcinogenesis - 1 Jan 1998

Lu J, Jiang C, Mitrenga T, Cutter G, Thompson H J

Abstract excerpt

The induction of mammary carcinogenesis in the rat by 1-methyl-1-nitrosourea (MNU) is widely used in experimental breast cancer research. In the experiments reported, the Ha-ras codon 12 (ras12) mutation (GGA-->GAA) was used as a molecular marker to address issues of the clonality of carcinomas induced, pathogenetic independence among multiple carcinomas within the same animal and topographic distribution of...

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Identifiers

PMID: 9472716
DOI: 10.1093/carcin/19.1.223

Genes

GAA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Pathogenic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat.PMID 9472716Read ↗

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