The association between phenotype and size of breast tumors induced by 1-methyl-1-nitrosourea (MNU) injection in rats.

Abstract excerpt

BACKGROUND: Administration of 1-methyl-1-nitrosourea (MNU) is considered a simple and rapid method for inducing breast tumors in rats. While most studies focus on the time frame of tumor development, there are little data on the development of breast tumor in relation to tumor size. Thus the current study was carried out to analyze the phenotype of MNU-induced tumors in relation to tumor size. MATERIAL/METHODS:...

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