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Article

Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2006

Quan Xiaojiang, Laes Jean-François, Stieber Daniel, Rivière Michèle, Russo Jose, Wedekind Dirk, Coppieters Wouter, Farnir Frédéric, Georges Michel, Szpirer Josiane, Szpirer Claude

Abstract excerpt

The rat is considered an excellent model for studying human breast cancer. Therefore, understanding the genetic basis of susceptibility to mammary cancer in this species is of great interest. Previous studies based on crosses involving the susceptible strain WF (crossed with the resistant strains COP or WKY) and focusing on tumor multiplicity as the susceptibility phenotype led to the identification of several...

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PMID: 16596452
DOI: 10.1007/s00335-005-0125-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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