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Article

Absence of Ras mutations in rat DMBA-induced mammary tumors.

Molecular carcinogenesis - 1 Feb 2009

Samuelson Emma, Nilsson Johanna, Walentinsson Anna, Szpirer Claude, Behboudi Afrouz

Abstract excerpt

Animal cancer models reduce genetic background heterogeneity and thus, may facilitate identification and analysis of specific genetic aberrations in tumor cells. Rat and human mammary glands have high similarity in physiology and show comparable hormone responsiveness. Thus, spontaneous and carcinogen (e.g., NMU and DMBA)-induced rat mammary models are valuable tools for genetic studies of breast cancer. In...

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Source

Identifiers

PMID: 18649354
DOI: 10.1002/mc.20464

Genes

NMU

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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