Article
Allele-specific expression of the Mgi- phenotype on disruption of the F1-ATPase delta-subunit gene in Kluyveromyces lactis.
Current genetics - 1 Jan 1998
Hansbro P M, Chen X J, Clark-Walker G D
Abstract excerpt
Kluyveromyces lactis is a petite-negative yeast that does not form viable mitochondrial genome-deletion mutants (petites) when treated with DNA-targeting drugs. Loss of mtDNA is lethal for this yeast but mutations at three loci termed MGI, for mitochondrial genome integrity, can suppress this let...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Fungal
- DNA, Mitochondrial
- Genes, Fungal
- Kluyveromyces
- Molecular Sequence Data
- Mutagenesis, Insertional
- Phenotype
- Proton-Translocating ATPases
- Sequence Analysis, DNA
- Species Specificity