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Article

The petite mutation in yeasts: 50 years on.

International review of cytology - 1 Jan 2000

Chen X J, Clark-Walker G D

Abstract excerpt

Fifty years ago it was reported that baker's yeast, Saccharomyces cerevisiae, can form "petite colonie" mutants when treated with the DNA-targeting drug acriflavin. To mark the jubilee of studies on cytoplasmic inheritance, a review of the early work will be presented together with some observations on current developments. The primary emphasis is to address the questions of how loss of mtDNA leads to lethality...

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Source

Identifiers

PMID: 10494627
DOI: 10.1016/s0074-7696(08)62397-9

Genes

PGS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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