Article
Cloning and characterization of the lipoyl-protein ligase gene LIPB from the yeast Kluyveromyces lactis: synergistic respiratory deficiency due to mutations in LIPB and mitochondrial F1-ATPase subunits.
Molecular & general genetics : MGG - 1 Jul 1997
Chen X J
Abstract excerpt
The mgi1-4 and mgi2-1 mutants of the petite-negative yeast Kluyveromyces lactis have mutations in the beta- and alpha-subunits of the mitochondrial F1-ATPase, respectively. The mutants are respiratory competent but can form petites with deletions in mitochondrial DNA. In this study a cryptic nucl...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Division
- Cloning, Molecular
- DNA, Mitochondrial
- Ethanol
- Fungal Proteins
- Genes, Fungal
- Glycine
- Kluyveromyces
- Mitochondria
- Molecular Sequence Data
- Mutation
- Oxygen Consumption
- Peptide Synthases
- Proton-Translocating ATPases
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid