Mutations in MGI genes convert Kluyveromyces lactis into a petite-positive yeast.

doi:10.1093/genetics/133.3.517

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Article

Mutations in MGI genes convert Kluyveromyces lactis into a petite-positive yeast.

Genetics - 1 Mar 1993

Chen X J, Clark-Walker G D

Abstract excerpt

Following targeted disruption of the unique CYC1 gene, the petite-negative yeast, Kluyveromyces lactis, was found to grow fermentatively in the absence of cytochrome c-mediated respiration. This observation encouraged us to seek mitochondrial mutants by treatment of K. lactis with ethidium bromid...

Topics

DNA, Fungal
DNA, Mitochondrial
Ethidium
Fermentation
Gene Deletion
Genes, Fungal
Kluyveromyces
Mutagenesis, Site-Directed
Phenotype
Plasmids

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