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Article

Mutations in MGI genes convert Kluyveromyces lactis into a petite-positive yeast.

Genetics - 1 Mar 1993

Chen X J, Clark-Walker G D

Abstract excerpt

Following targeted disruption of the unique CYC1 gene, the petite-negative yeast, Kluyveromyces lactis, was found to grow fermentatively in the absence of cytochrome c-mediated respiration. This observation encouraged us to seek mitochondrial mutants by treatment of K. lactis with ethidium bromide at the highest concentration permitting survival. By this technique, we isolated four mtDNA mutants, three lacking...

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Source

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Identifiers

PMID: 8454202
DOI: 10.1093/genetics/133.3.517
PMCID: PMC1205340

Genes

CYC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in MGI genes convert Kluyveromyces lactis into a petite-positive yeast.PMID 8454202Read ↗

A vital function for mitochondrial DNA in the petite-negative yeast Kluyveromyces lactis.Semantic proximity Read ↗

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Suppression of rho0 lethality by mitochondrial ATP synthase F1 mutations in Kluyveromyces lactis occurs in the absence of F0.Semantic proximity Read ↗

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