Article
Absence of F1-ATPase activity in Kluyveromyces lactis lacking the epsilon subunit.
Current genetics - 1 Jul 2000
Chen X J
Abstract excerpt
The mitochondrial F1-ATPase is a multimeric enzyme, comprised of 3alpha, 3beta, gamma, delta and epsilon subunits, that is primarily responsible for the synthesis of ATP in eukaryotic cells. Recent work has shown that the F1 complex of the petite-negative yeast Kluyveromyces lactis, with specific mutations in the alpha, beta or gamma subunits, has a novel function that suppresses lethality caused by loss of...
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