Article
Effect of frameshift-inducing mutants of elongation factor 1alpha on programmed +1 frameshifting in yeast.
RNA (New York, N.Y.) - 1 Jan 1998
Farabaugh P J, Vimaladithan A
Abstract excerpt
The translational apparatus very efficiently eliminates errors that would cause a spontaneous shift in frames. The probability of frameshifting can be increased dramatically by either cis or trans-acting factors. Programmed translational frameshift sites are cis-acting sequences that greatly increase the frequency of such errors, at least in part by causing a transient translational pause. Pausing during...
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