Article

RNA elements required for the high efficiency of West Nile Virus-induced ribosomal frameshifting

2024-10-16

Abstract excerpt

West Nile Virus (WNV), a member of the Flaviviridae family, requires programmed -1 ribosomal frameshifting (PRF) for translation of the viral genome. The efficiency of WNV frameshifting is among the highest observed to date. Despite structural similarities to frameshifting sites in other viruses, it remains unclear why WNV exhibits such a high frameshifting efficiency. Here we employed dual-luciferase reporter as...

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Literature Corpus work: cac952bd-5699-56be-a14d-1658ce778ada
DOI: 10.1101/2024.10.16.618579

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