Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nonsense-mediated decay mutants do not affect programmed -1 frameshifting.

RNA (New York, N.Y.) - 1 Jul 2000

Bidou L, Stahl G, Hatin I, Namy O, Rousset J P, Farabaugh P J

Abstract excerpt

Sequences in certain mRNAs program the ribosome to undergo a noncanonical translation event, translational frameshifting, translational hopping, or termination readthrough. These sequences are termed recoding sites, because they cause the ribosome to change temporarily its coding rules. Cis and trans-acting factors sensitively modulate the efficiency of recoding events. In an attempt to quantitate the effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to Escherichia coli
Share to Frameshift Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Plasmids

Share to Protein Biosynthesis

Share to Saccharomyces cerevisiae

Share to Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 10917592
DOI: 10.1017/s1355838200000443
PMCID: PMC1369972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nonsense-mediated decay mutants do not affect programmed -1 frameshifting.PMID 10917592Read ↗

Hidden stop codons orchestrate mRNA fate by ambushing ribosomal frameshifting associated with codon usageSemantic proximity Read ↗

mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.Semantic proximity Read ↗

Therapeutic promise of engineered nonsense suppressor tRNAs.Semantic proximity Read ↗

Nonsense-mediated mRNA decayin health and diseaseSemantic proximity Read ↗

CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replicationSemantic proximity Read ↗

Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae.Semantic proximity Read ↗

The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed –1 ribosomal frameshiftingSemantic proximity Read ↗

Identification of Hepta- and Octo-Uridine stretches as sole signals for programmed +1 and -1 ribosomal frameshifting during translation of SARS-CoV ORF 3a variants.Semantic proximity Read ↗

Modulation of efficiency of translation termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

Poor codon optimality as a signal to degrade transcripts with frameshiftsSemantic proximity Read ↗

ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosisSemantic proximity Read ↗

Ribosome recycling factor ABCE1 depletion inhibits nonsense-mediated mRNA decay by promoting stop codon readthroughSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.