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Article

Impact of adjustments for intermediate phenotypes on the power to detect linkage.

Genetic epidemiology - 1 Jan 1997

Arnett D K, Pankow J S, Atwood L D, Sellers T A

Abstract excerpt

Since the manifestation of a complex disease is likely to be influenced through multiple genetic and/or environmental pathways, it may be advantageous to adjust for these multiple factors in a genetic analysis of a complex quantitative trait. Sib-pair linkage analysis was performed on the simulated complex quantitative trait Q1 after adjustment for age, sex, and the environmental factor (i.e., minimally adjusted)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9433572
DOI: 10.1002/(SICI)1098-2272(1997)14:6<749::AID-GEPI31>3.0.CO;2-O

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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