Article
Detection of susceptibility genes as modifiers due to subgroup differences in complex disease.
European journal of human genetics : EJHG - 1 Aug 2010
Bergen Sarah E, Maher Brion S, Fanous Ayman H, Kendler Kenneth S
Abstract excerpt
Complex diseases invariably involve multiple genes and often exhibit variable symptom profiles. The extent to which disease symptoms, course, and severity differ between affected individuals may result from underlying genetic heterogeneity. Genes with modifier effects may or may not also influenc...
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