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Article

Impact of preadjusting a quantitative phenotype prior to sib-pair linkage analysis when gene x environment interaction exists.

Genetic epidemiology - 1 Jan 2001

Mosley J, Conti D V, Elston R C, Witte J S

Abstract excerpt

The investigation of potential gene x environment (G x E) interactions is an important facet in the study of complex diseases. When G x E interaction exists, linkage analyses of the interacting gene must treat the environmental factor appropriately. Specifically, the common approach of regressing out an environmental factor prior to linkage analysis may be inappropriate if that factor has an interaction with the...

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Identifiers

PMID: 11793789
DOI: 10.1002/gepi.2001.21.s1.s837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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