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Article

Urinary excretion of codeine, ethylmorphine, and their metabolites: relation to the CYP2D6 activity.

Therapeutic drug monitoring - 1 Dec 1997

Hedenmalm K, Sundgren M, Granberg K, Spigset O, Dahlqvist R

Abstract excerpt

The formation of morphine from codeine and ethylmorphine is mainly mediated by the polymorphic enzyme CYP2D6. The objective of this study was to investigate whether CYP2D6 poor metabolizers (PM) and CYP2D6 extensive metabolizers (EM) would respond differently during testing for opiate drugs of abuse in urine after intake of these drugs. Five PM and five EM of dextromethorphan were administered single oral doses...

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Identifiers

PMID: 9421105
DOI: 10.1097/00007691-199712000-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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