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Article

CYP2D6 phenotype-specific codeine population pharmacokinetics.

Journal of pain & palliative care pharmacotherapy - 1 Mar 2015

Linares Oscar A, Fudin Jeffrey, Schiesser William E, Daly Linares Annemarie L, Boston Raymond C

Abstract excerpt

Codeine's metabolic fate in the body is complex, and detailed quantitative knowledge of it, and that of its metabolites is lacking among prescribers. We aimed to develop a codeine pharmacokinetic pathway model for codeine and its metabolites that incorporates the effects of genetic polymorphisms. We studied the phenotype-specific time courses of plasma codeine, codeine-6-glucoronide, morphine,...

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Share to Analgesics, Opioid
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25562725
DOI: 10.3109/15360288.2014.997854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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