Article
On the assessment of drug metabolism by assays of codeine and its main metabolites.
Therapeutic drug monitoring - 1 Jun 2000
Haffen E, Paintaud G, Berard M, Masuyer C, Bechtel Y, Bechtel P R
Abstract excerpt
Codeine and its main metabolites appear to have advantages for assessing drug metabolic phenotypes. The authors have further developed a high-performance liquid chromatography (HPLC) method for the quantification of codeine and six of its metabolites in urine. Quantification was performed by electrochemical detection for morphine, normorphine, morphine-6-glucuronide, and the internal standard 4-O-methyldopamine;...
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