Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exclusion of BBC1 and CMAR as candidate breast tumour-suppressor genes.

British journal of cancer - 1 Jan 1997

Moerland E, Breuning M H, Cornelisse C J, Cleton-Jansen A M

Abstract excerpt

Loss of heterozygosity (LOH) on chromosome arm 16q occurs in 48-65% of breast tumours. One small region of overlap is located at 16q24.3. Two genes located in this region, the cellular adhesion regulatory molecule (CMAR) and the breast basic conserved gene (BBC1), are plausible candidate tumour-suppressor genes. Mutational analysis of the retained copy of these genes has been performed by direct sequencing in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Adhesion Molecules
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Loss of Heterozygosity

Share to Mutation

Share to Neoplasm Proteins

Share to Polymorphism, Genetic

Share to Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 9413939
DOI: 10.1038/bjc.1997.594
PMCID: PMC2228200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exclusion of BBC1 and CMAR as candidate breast tumour-suppressor genes.PMID 9413939Read ↗

Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes.Semantic proximity Read ↗

Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locusSemantic proximity Read ↗

The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.Semantic proximity Read ↗

Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread.Semantic proximity Read ↗

The frequency and mechanism of loss of heterozygosity on chromosome 11q in breast cancer.Semantic proximity Read ↗

ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism.Semantic proximity Read ↗

Loss of heterozygosity on chromosome 11 q in breast cancer.Semantic proximity Read ↗

Loss of heterozygosity in human breast carcinomas in the ataxia telangiectasia, Cowden disease and BRCA1 gene regions.Semantic proximity Read ↗

Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma.Semantic proximity Read ↗

E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast.Semantic proximity Read ↗

Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation.Semantic proximity Read ↗

Altered expression of E-cadherin in breast cancer. patterns, mechanisms and clinical significance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.