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Article

The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 2003

Martin Eric S, Cesari Rossano, Pentimalli Francesca, Yoder Kristine, Fishel Richard, Himelstein Andrew L, Martin S Eric, Godwin Andrew K, Negrini Massimo, Croce Carlo M

Abstract excerpt

Frequent allelic loss at human chromosome 11q23-q24 occurs in a wide variety of cancers, suggesting that this region may harbor a tumor suppressor gene. By constructing a physical map of the LOH11CR2 minimal region of loss on 11q23-q24 associated with lung and breast carcinomas, we were able to clone a hereditary translocation, t(11;12)(q23;q24), in a patient with early-onset breast cancer and family history of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 14504409
DOI: 10.1073/pnas.1934602100
PMCID: PMC208790

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.PMID 14504409Read ↗

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