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Article

Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread.

Cancer research - 15 Jan 1994

Tsuda H, Callen D F, Fukutomi T, Nakamura Y, Hirohashi S

Abstract excerpt

Loss of heterozygosity on chromosomal arm 16q has been shown to be a frequent event in sporadic breast cancer and is suggested to be involved in cancer development through inactivation of a tumor-suppressor gene. To specify the commonly deleted region in which the unknown tumor-suppressor gene is located, a deletion map of chromosome 16 was constructed for 78 breast cancers, using 27 polymorphic DNA markers. Loss...

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PMID: 8275489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread.PMID 8275489Read ↗

Allelic imbalance study of 16q in human primary breast carcinomas using microsatellite markers.Semantic proximity Read ↗

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Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas.Semantic proximity Read ↗

Loss of heterozygosity on the long arm of chromosome 6 in breast cancer: possibly four regions of deletion.Semantic proximity Read ↗

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