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Article

The frequency and mechanism of loss of heterozygosity on chromosome 11q in breast cancer.

The Journal of pathology - 1 Sept 1996

Tomlinson I P, Nicolai H, Solomon E, Bodmer W F

Abstract excerpt

Loss of heterozygosity (LOH, allele loss) occurs frequently on the long arm of chromosome 11 in breast cancer. Seventy-one paired tumour/normal DNA samples from breast cancer patients under 50 years old were studied for allele loss at four microsatellite loci on 11q: D11S29 (11q23.3), NCAM (11q22-q23), D11S968 (11qtel), and D11S1313 (11qcen). The maximum frequency of LOH (approximately 35 per cent) was found at...

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Identifiers

PMID: 8943813
DOI: 10.1002/(SICI)1096-9896(199609)180:1<38::AID-PATH638>3.0.CO;2-C

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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