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Article

Loss of heterozygosity in human breast carcinomas in the ataxia telangiectasia, Cowden disease and BRCA1 gene regions.

Oncogene - 23 Jan 1997

Kerangueven F, Eisinger F, Noguchi T, Allione F, Wargniez V, Eng C, Padberg G, Theillet C, Jacquemier J, Longy M, Sobol H, Birnbaum D

Abstract excerpt

To appreciate the involvement of known or potential susceptibility genes in sporadic breast tumors, we have searched for chromosomal deletions by studying loss of heterozygosity (LOH) at 43 microsatellite (CA)n markers from human chromosomes 10, 11 and 17, in 115 unselected consecutive samples of breast carcinoma with particular emphasis on specific regions. No site of consistent LOH was identified on chromosome...

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Source

Identifiers

PMID: 9018120
DOI: 10.1038/sj.onc.1200818

Genes

BRCA1
ATM
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of heterozygosity in human breast carcinomas in the ataxia telangiectasia, Cowden disease and BRCA1 gene regions.PMID 9018120Read ↗

Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas.Semantic proximity Read ↗

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Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified.Semantic proximity Read ↗

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Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomas.Semantic proximity Read ↗

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