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Article

Altered expression of E-cadherin in breast cancer. patterns, mechanisms and clinical significance.

European journal of cancer (Oxford, England : 1990) - 1 Jun 2000

Asgeirsson K S, Jónasson J G, Tryggvadóttir L, Olafsdóttir K, Sigurgeirsdóttir J R, Ingvarsson S, Ogmundsdóttir H M

Abstract excerpt

Reduced cell adhesion brought about by altered surface expression of E-cadherin has been implicated in invasive and metastatic malignant growth. We investigated the patterns of immunohistochemical E-cadherin expression in 120 breast carcinomas. Furthermore, we analysed DNA from the same samples for loss of heterozygosity (LOH) using three separate microsatellite markers on chromosome 16q22.1. Finally, the...

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PMID: 10854942
DOI: 10.1016/s0959-8049(00)00062-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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