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Article

Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11.

Anticancer research - 1 Jan 2000

O'Briant K, Jolicoeur E, Garst J, Campa M, Schreiber G, Bepler G

Abstract excerpt

Two regions on chromosome segment 11p15.5 have frequent allele loss in lung cancer. LOH11A is centromeric between loci D11S1758 and D11S12, and LOH11B is telomeric between HRAS and D11S1363. We studied the biological significance of this allele loss using microcell-mediated transfer of human chromosomes 11, 11p, and two radiation-reduced fragments of 11p into human lung adenocarcinoma cell lines. Chromosome 12,...

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Source

Identifiers

PMID: 9413155

Genes

HRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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